VRK1 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI2E10]
Specifications
| Product Data | |
| Clone Name | OTI2E10 |
|---|---|
| Application | WB |
| Recommended Dilution | WB 1:2000 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1-230 of human VRK1(NP_003375) produced in E.coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol. |
| Concentration | 0.5 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | HRP |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 45.3 kDa |
| Gene Name | vaccinia related kinase 1 |
| Database Link | |
| Background | This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN. provided by RefSeq, Jul 2008 |
| Synonyms | PCH1; PCH1A |
| Reference Data | |
| Protein Categories | Enzyme: Kinases, Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome, Protein Kinase |
Reviews
Documents
| Product Manuals |
| FAQs |
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Resources
Other "OTI2E10" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF805791 | Carrier-free (BSA/glycerol-free) VRK1 mouse monoclonal antibody, clone OTI2E10 (formerly 2E10) | 100 ug |
$620.00
|
|
| TA805791 | VRK1 mouse monoclonal antibody, clone OTI2E10 (formerly 2E10) | 100 ul |
$447.00
|
|
| TA805791AM | VRK1 mouse monoclonal antibody, clone OTI2E10 (formerly 2E10), Biotinylated | 100 ul |
$509.00
|
|
| TA805791S | VRK1 mouse monoclonal antibody, clone OTI2E10 (formerly 2E10) | 30 ul |
$200.00
|
|
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