SAV1 Mouse Monoclonal Antibody [Clone ID: OTI7C7]
Specifications
| Product Data | |
| Clone Name | OTI7C7 |
|---|---|
| Application | WB |
| Recommended Dilution | WB 1:2000 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 167-383 of human SAV1 (NP_068590) produced in E.coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 44.5 kDa |
| Gene Name | salvador family WW domain containing protein 1 |
| Database Link | |
| Background | WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor. [provided by RefSeq, Aug |
| Synonyms | SAV; WW45; WWP4 |
| Reference Data | |
| Protein Categories | Growth Factors, Intracellular Proteins |
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Other "OTI7C7" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF804928 | Carrier-free (BSA/glycerol-free) SAV1 mouse monoclonal antibody, clone OTI7C7 (formerly 7C7) | 100 ug |
$620.00
|
|
| TA804928 | SAV1 mouse monoclonal antibody, clone OTI7C7 (formerly 7C7) | 100 ul |
$447.00
|
|
| TA804928AM | SAV1 mouse monoclonal antibody, clone OTI7C7 (formerly 7C7), Biotinylated | 100 ul |
$509.00
|
|
| TA804928BM | SAV1 mouse monoclonal antibody, clone OTI7C7 (formerly 7C7), HRP conjugated | 100 ul |
$509.00
|
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