Angiotensin Converting Enzyme 2 (ACE2) Mouse Monoclonal Antibody [Clone ID: OTI4D2]

CAT#: TA803841

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ACE2 mouse monoclonal antibody, clone OTI4D2 (formerly 4D2)



  View other "OTI4D2" antibodies (2)

USD 379.00


Availability*
In Stock

Size
    • 100 ul


Specifications

Product Data
Clone Name OTI4D2
Applications IHC, WB
Recommended Dilution WB 1:200, IHC 1:150
Reactivity Human
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 18-237 of human ACE2 (NP_068576) produced in E.coli.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name angiotensin I converting enzyme 2
Background The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq, Jul 2008]
Synonyms ACEH
Reference Data
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways Renin-angiotensin system

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