WNT3 Mouse Monoclonal Antibody [Clone ID: OTI3G5]

CAT#: TA801892

WNT3 mouse monoclonal antibody,clone OTI3G5

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 Product Datasheet for 'TA801892'

USD 350


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Size
    • 100 ul

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Specifications

Product Data
Clone Name OTI3G5
Applications WB, IHC
Recommend Dilution WB 1:2000, IHC 1:150,
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 128-355 of human WNT3 (NP_110380) produced in E.coli.
Isotype IgG2b
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids by affinity chromatography
Predicted Protein Size 37.4 kDa
Gene Name Wnt family member 3
Background The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region. [provided by RefSeq, Jul 2008].
Synonyms INT4|TETAMS
Reference Data
Protein Families Secreted Protein, Transmembrane, Druggable Genome
Protein Pathways Wnt signaling pathway, Hedgehog signaling pathway, Melanogenesis, Pathways in cancer, Basal cell carcinoma
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.