RASGRP3 Mouse Monoclonal Antibody [Clone ID: OTI2C11]

CAT#: TA801533

Reviews ()
Write a review

RASGRP3 mouse monoclonal antibody, clone OTI2C11 (formerly 2C11)



  View other "OTI2C11" antibodies (4)

Special Offer: Try sample size of this antibody at $99/€99. Use code “TrueSample”.

USD 417.00


Availability*
In Stock

Size
    • 100 ul


Specifications

Product Data
Clone Name OTI2C11
Applications IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 380-690 of human RASGRP3 (NP_733772) produced in E.coli.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 78.2 kDa
Gene Name RAS guanyl releasing protein 3
Background Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]). [supplied by OMIM, Mar 2008]
Synonyms GRP3
Reference Data
Protein Pathways B cell receptor signaling pathway, MAPK signaling pathway

Other Versions

Other products for "RASGRP3"
Frequently bought together (2)
Transient overexpression lysate of RAS guanyl releasing protein 3 (calcium and DAG-regulated) (RASGRP3), transcript variant 2
    • 100 ug

USD 396.00


beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

USD 186.00

Customer Reviews 
Loading...
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.