E Cadherin (CDH1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2D6]

CAT#: TA800669AM

CDH1 mouse monoclonal antibody,clone 2D6, Biotinylated

Conjugation: Unconjugated Biotin HRP


  View other "OTI2D6" antibodies (4)

USD 509.00

5 Days*

Size
    • 100 ul

Frequently bought together (3)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

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Recombinant protein of human cadherin 1, type 1, E-cadherin (epithelial) (CDH1), 20 µg
    • 20 ug

USD 867.00


Transient overexpression lysate of cadherin 1, type 1, E-cadherin (epithelial) (CDH1)
    • 100 ug

USD 665.00

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Specifications

Product Data
Clone Name OTI2D6
Applications IHC, WB
Recommended Dilution WB 1:2000
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human CDH1 (NP_004351) produced in HEK293T cell.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Biotin
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 94.8 kDa
Gene Name cadherin 1
Background This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008]
Synonyms Arc-1; CD324; CDHE; ECAD; LCAM; UVO
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Adherens junction, Bladder cancer, Cell adhesion molecules (CAMs), Endometrial cancer, Melanoma, Pathogenic Escherichia coli infection, Pathways in cancer, Thyroid cancer

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.