APE1(APEX1) Mouse Monoclonal Antibody [Clone ID: OTI4D9]

CAT#: TA800336

APEX1 mouse monoclonal antibody, clone OTI4D9 (formerly 4D9)

Antibody Service

 Product Datasheet for 'TA800336'

USD 379.00

In Stock

    • 100 ul

Product images


Product Data
Clone Name OTI4D9
Applications WB, IHC
Recommend Dilution WB 1:2000, IHC 1:150,
Reactivity Human , Dog , Rat , Monkey , Mouse
Host Mouse
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 1-242 of human APEX1 (NP_001632) produced in E.coli.
Isotype IgG2b
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids by affinity chromatography
Predicted Protein Size 35.4 kDa
Gene Name apurinic/apyrimidinic endodeoxyribonuclease 1
Background Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq, Jul 2008].
Reference Data
Protein Families Stem cell - Pluripotency, Transcription Factors, Druggable Genome
Protein Pathways Base excision repair
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.