Chk1 (CHEK1) Rabbit Monoclonal Antibody [Clone ID: OTIR3G7]

CAT#: TA591044

Rabbit monoclonal anti-CHK1 antibody for SISCAPA, clone OTIR3G7


USD 516.00

In Stock*

Size
    • 100 ul

Product Images

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Specifications

Product Data
Clone Name OTIR3G7
Applications SISCAPA
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Monoclonal
Immunogen Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human CHEK1 (NP_001265). The exact sequence is proprietary.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration Lot dependent; please refer to CoA along with shipment
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 54.4 kDa
Gene Name checkpoint kinase 1
Background The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011]
Synonyms CHK1
Reference Data
Protein Families Druggable Genome, Protein Kinase, Stem cell - Pluripotency
Protein Pathways Cell cycle, p53 signaling pathway

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