SM22 alpha (TAGLN) Rabbit Monoclonal Antibody [Clone ID: OTIR1F8]

CAT#: TA591013

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Rabbit monoclonal anti-TAGL antibody for SISCAPA, clone OTIR1F8



USD 428.00


Availability*
In Stock

Size
    • 100 ul


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Specifications

Product Data
Clone Name OTIR1F8
Applications SISCAPA
Reactivity Human
Host Rabbit
Isotype IgG
Clonality Monoclonal
Immunogen Synthetic peptide AAEDYGVIK
Formulation Tissue culture buffer containing 1% BSA and 0.02% Sodium azide
Concentration Lot dependent; please refer to CoA along with shipment
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 22.4 kDa
Gene Name transgelin
Background This gene encodes a shape change and transformation sensitive actin-binding protein which belongs to the calponin family. It is ubiquitously expressed in vascular and visceral smooth muscle, and is an early marker of smooth muscle differentiation. The encoded protein is thought to be involved in calcium-independent smooth muscle contraction. It acts as a tumor suppressor, and the loss of its expression is an early event in cell transformation and the development of some tumors, coinciding with cellular plasticity. The encoded protein has a domain architecture consisting of an N-terminal calponin homology (CH) domain and a C-terminal calponin-like (CLIK) domain. Mice with a knockout of the orthologous gene are viable and fertile but their vascular smooth muscle cells exhibit alterations in the distribution of the actin filament and changes in cytoskeletal organization. [provided by RefSeq, Aug 2017]
Synonyms SM22; Sm22; Sm22a; Ws310
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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