PTPRB Rabbit Polyclonal Antibody

CAT#: TA590670

Rabbit Polyclonal PTPRB Antibody

Antibody Service

 Product Datasheet for 'TA590670'

USD 409.00

In Stock

    • 100 ug

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Product Data
Clone Name Polyclonal
Applications ELISA
Recommend Dilution ELISA: 1:5000-1:20000
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen DNA immunization. This antibody is specific for the N Terminus Region of the target protein.
Isotype IgG
Formulation 20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Concentration 1 mg/ml
Purification The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Gene Name protein tyrosine phosphatase, receptor type B
Background PTPRB is a member of the protein tyrosine phosphatase (PTP) family. The family comprises at least 37 proteins, characterized by a catalytic phosphatase domain of approximately 240 amino acids, and includes both transmembrane and cytosolic enzymes. PTP1B is a transmembrane PTP. The PTPs have high substrate specificity for phosphotyrosyl proteins, at the primary sequence level sharing little similarity with the protein serine phosphatases, protein threonine phosphatases, or the acid and alkaline phosphatases. PTP beta interacts with and regulates the tyrosine phosphorylation level of catenins, which are critical in physiological and pathological events such as cell migration, adhesion and transformation.
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT
Reference Data
Protein Families Phosphatase, Druggable Genome
Protein Pathways Adherens junction
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