Estrogen Receptor beta (ESR2) Rabbit Polyclonal Antibody
Rabbit Polyclonal Estrogen Receptor beta Antibody
Product Datasheet for 'TA590082'
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|Recommend Dilution||WB: 1:5000-1:20000; ELISA: 1:100-1:2000; IHC: 1:10-1:2000; IHC-P 1:250-1:2000; IP 1:10-1:500|
|Immunogen||DNA immunization. This antibody is specific for the N Terminus Region of the target protein.|
|Formulation||20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0|
|Purification||The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.|
|Gene Name||estrogen receptor 2|
|Background||This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq]|
|Synonyms||ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2|
|Note||This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT|
|Protein Families||Druggable Genome, Nuclear Hormone Receptor, Transcription Factors|