HPRT(HPRT1) Mouse Monoclonal Antibody [Clone ID: OTI2H5]
HPRT1 mouse monoclonal antibody, clone OTI2H5 (formerly 2H5)
Product Datasheet for 'TA506953'
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|Recommend Dilution||WB 1:4000,|
|Immunogen||Full length human recombinant protein of human HPRT1(NP_000185) produced in HEK293T cell.|
|Formulation||PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purification||Purified from mouse ascites fluids by affinity chromatography|
|Predicted Protein Size||24.4 kDa|
|Gene Name||hypoxanthine phosphoribosyltransferase 1|
|Background||The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.[provided by RefSeq, Jun 2009].|
|Protein Families||Stem cell - Pluripotency, Druggable Genome|
|Protein Pathways||Purine metabolism, Drug metabolism - other enzymes, Metabolic pathways|