PDGF Receptor beta (PDGFRB) Mouse Monoclonal Antibody [Clone ID: OTI1D1]
PDGFRB mouse monoclonal antibody, clone OTI1D1 (formerly 1D1)
Product Datasheet for 'TA506226'
|Recommend Dilution||WB 1:1000, IF 1:100|
|Immunogen||Full length human recombinant protein of human PDGFRB(RNP_002600) produced in HEk293T cell.|
|Formulation||PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purification||Purified from cell culture supernatant by affinity chromatography|
|Predicted Protein Size||123.8 kDa|
|Gene Name||platelet derived growth factor receptor beta|
|Background||This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Jul 2008]|
|Synonyms||CD140B; IBGC4; IMF1; JTK12; KOGS; PDGFR; PDGFR-1; PDGFR1; PENTT|
|Protein Families||Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Transmembrane|
|Protein Pathways||Calcium signaling pathway, Colorectal cancer, Cytokine-cytokine receptor interaction, Focal adhesion, Gap junction, Glioma, MAPK signaling pathway, Melanoma, Pathways in cancer, Prostate cancer, Regulation of actin cytoskeleton|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.