HGS Mouse Monoclonal Antibody [Clone ID: OTI1C2]

CAT#: TA505832

HGS mouse monoclonal antibody, clone OTI1C2 (formerly 1C2)

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HGS (RC200609, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HGS. Positive lysates LY401488 (100ug) and LC401488 (20ug) can be purchased separately from OriGene.

Specifications

Product Data

• Clone Name: OTI1C2
• Applications: WB
• Recommended Dilution: WB 1:2000
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human HGS (NP_004703) produced in HEK293T cell.
• Formulation: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 86 kDa
• Gene Name: hepatocyte growth factor-regulated tyrosine kinase substrate
• Database Link:
  NP_004703
  Entrez Gene 15239 MouseEntrez Gene 56084 RatEntrez Gene 9146 Human
  UniProt ID O14964
• Background: The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation. [provided by RefSeq, Dec 2010]
• Synonyms: HRS

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Endocytosis