Asialoglycoprotein Receptor 2(ASGR2) Mouse Monoclonal Antibody [Clone ID: OTI4B6]

CAT#: TA505266

ASGR2 (Asialoglycoprotein Receptor 2) mouse monoclonal antibody, clone OTI4B6 (formerly 4B6)

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 Product Datasheet for 'TA505266'

USD 350.00

In Stock

    • 100 ul

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Product Data
Clone Name OTI4B6
Applications WB, IF
Recommend Dilution WB 1:4000, IF 1:100,
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human ASGR2(NP_001172) produced in HEK293T cell.
Isotype IgG2b
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids by affinity chromatography
Predicted Protein Size 35 kDa
Gene Name asialoglycoprotein receptor 2
Background This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011].
Reference Data
Protein Families Transmembrane, Druggable Genome
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