UBE2G2 Mouse Monoclonal Antibody [Clone ID: OTI4D6]
UBE2G2 mouse monoclonal antibody, clone OTI4D6 (formerly 4D6)
Product Datasheet for 'TA505263'
|Applications||IF, IHC, WB|
|Recommend Dilution||WB 1:200~4000, IHC 1:150, IF 1:100|
|Reactivity||Human, Monkey, Mouse, Rat, Dog|
|Immunogen||Full length human recombinant protein of human UBE2G2(NP_003334) produced in HEK293T cell.|
|Formulation||PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purification||Purified from mouse ascites fluids by affinity chromatography|
|Predicted Protein Size||18.4 kDa|
|Gene Name||ubiquitin conjugating enzyme E2 G2|
|Background||The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse counterpart. This gene is ubiquitously expressed, with high expression seen in adult muscle. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jan|
|Protein Families||Druggable Genome|
|Protein Pathways||Parkinson's disease, Ubiquitin mediated proteolysis|
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