SOCS3 Mouse Monoclonal Antibody [Clone ID: OTI3B8]
$447.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI3B8 |
|---|---|
| Application | FC, IF, WB |
| Recommended Dilution | WB 1:2000, IF 1:100, FLOW 1:100 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human SOCS3 (NP_003946) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 0.83 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 24.6 kDa |
| Gene Name | suppressor of cytokine signaling 3 |
| Database Link | |
| Background | This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. provided by RefSeq |
| Synonyms | ATOD4; CIS3; Cish3; SOCS-3; SSI-3; SSI3 |
| Note | WB application:Only overexpression results are guaranteed, not endogenous |
| Reference Data | |
| Protein Categories | Cytokines, Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Adipocytokine signaling pathway, Insulin signaling pathway, Jak-STAT signaling pathway, Type II diabetes mellitus, Ubiquitin mediated proteolysis |
Reviews
Documents
| Product Manuals |
| FAQs |
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Resources
Other "OTI3B8" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF503055 | Carrier-free (BSA/glycerol-free) SOCS3 mouse monoclonal antibody, clone OTI3B8 (formerly 3B8) | 100 ug |
$620.00
|
|
| TA503055AM | SOCS3 mouse monoclonal antibody, clone OTI3B8 (formerly 3B8), Biotinylated | 100 ul |
$509.00
|
|
| TA503055BM | SOCS3 mouse monoclonal antibody, clone OTI3B8 (formerly 3B8), HRP conjugated | 100 ul |
$509.00
|
|
| TA503055S | SOCS3 mouse monoclonal antibody, clone OTI3B8 (formerly 3B8) | 30 ul |
$200.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
