STAT5A Mouse Monoclonal Antibody [Clone ID: OTI9F7]
CAT#: TA502736
STAT5A mouse monoclonal antibody, clone OTI9F7 (formerly 9F7)
Size: 30 ul
Formulation: Carrier-Free
USD 436.00
USD 867.00
Specifications
Product Data | |
Clone Name | OTI9F7 |
Applications | FC, IF, IHC, WB |
Recommended Dilution | WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100 |
Reactivities | Human, Dog, Rat, Monkey, Mouse |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human STAT5A (NP_003143) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | Lot dependent |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 90.5 kDa |
Gene Name | signal transducer and activator of transcription 5A |
Database Link | |
Background | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq] |
Synonyms | MGF; STAT5 |
Reference Data | |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Stem cell relevant signaling - JAK/STAT signaling pathway, Transcription Factors |
Protein Pathways | Acute myeloid leukemia, Chronic myeloid leukemia, ErbB signaling pathway, Jak-STAT signaling pathway, Pathways in cancer |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF502736 | Carrier-free (BSA/glycerol-free) STAT5A mouse monoclonal antibody, clone OTI9F7 (formerly 9F7) |
USD 600.00 |
|
TA502736AM | STAT5A mouse monoclonal antibody, clone OTI9F7 (formerly 9F7), Biotinylated |
USD 509.00 |
|
TA502736BM | STAT5A mouse monoclonal antibody, clone OTI9F7 (formerly 9F7), HRP conjugated |
USD 509.00 |
|
TA502736S | STAT5A mouse monoclonal antibody, clone OTI9F7 (formerly 9F7) |
USD 200.00 |
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