STAT5A Mouse Monoclonal Antibody [Clone ID: OTI9F7]

CAT#: TA502736

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STAT5A mouse monoclonal antibody, clone OTI9F7 (formerly 9F7)

Size: 30 ul 100 ul

Formulation: Standard Carrier-Free

Conjugation: Unconjugated Biotin HRP



USD 447.00

In Stock*

Size
    • 100 ul

Frequently bought together (3)
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Specifications

Product Data
Clone Name OTI9F7
Applications FC, IF, IHC, WB
Recommended Dilution WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivities Human, Dog, Rat, Monkey, Mouse
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human STAT5A (NP_003143) produced in HEK293T cell.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration Lot dependent
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 90.5 kDa
Gene Name signal transducer and activator of transcription 5A
Background The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq]
Synonyms MGF; STAT5
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Stem cell relevant signaling - JAK/STAT signaling pathway, Transcription Factors
Protein Pathways Acute myeloid leukemia, Chronic myeloid leukemia, ErbB signaling pathway, Jak-STAT signaling pathway, Pathways in cancer
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.