DCK Mouse Monoclonal Antibody [Clone ID: OTI16E12]
DCK mouse monoclonal antibody, clone OTI16E12 (formerly 16E12)
Product Datasheet for 'TA502650'
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|Recommend Dilution||WB 1:2000, FLOW 1:100|
|Immunogen||Full length human recombinant protein of human DCK (NP_000779) produced in HEK293T cell.|
|Formulation||PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purification||Purified from cell culture supernatant by affinity chromatography|
|Predicted Protein Size||30.3 kDa|
|Gene Name||deoxycytidine kinase|
|Background||Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq].|
|Protein Families||Druggable Genome|
|Protein Pathways||Purine metabolism, Pyrimidine metabolism|