DCK Mouse Monoclonal Antibody [Clone ID: OTI16E12]

CAT#: TA502650

DCK mouse monoclonal antibody, clone OTI16E12 (formerly 16E12)


 Product Datasheet for 'TA502650'

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USD 350.00


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Size
    • 100 ul

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Specifications

Product Data
Clone Name OTI16E12
Applications WB, FC
Recommend Dilution WB 1:2000, FLOW 1:100
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human DCK (NP_000779) produced in HEK293T cell.
Isotype IgG1
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1.00mg/ml
Purification Purified from cell culture supernatant by affinity chromatography
Predicted Protein Size 30.3 kDa
Gene Name deoxycytidine kinase
Background Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq].
Synonyms -
Reference Data
Protein Families Druggable Genome
Protein Pathways Purine metabolism, Pyrimidine metabolism
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