GBA3 Mouse Monoclonal Antibody [Clone ID: OTI4C7]

CAT#: TA502603S

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GBA3 mouse monoclonal antibody, clone OTI4C7 (formerly 4C7)



  View other "OTI4C7" antibodies (2)

USD 159.00


Availability*
2 Days

Size
    • 30 ul


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Specifications

Product Data
Clone Name OTI4C7
Applications FC, WB
Recommended Dilution WB 1:2000, FLOW 1:100
Reactivity Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 1-150 and 370-469 of human GBA3 (NP_066024) produced in E.coli.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.75 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 53.5 kDa
Gene Name glucosylceramidase beta 3 (gene/pseudogene)
Background GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides (de Graaf et al., 2001 [PubMed 11389701]). GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism (Hayashi et al., 2007 [PubMed 17595169]). [supplied by OMIM]
Synonyms CBG; CBGL1; GLUC; KLRP
Reference Data
Protein Pathways Cyanoamino acid metabolism, Starch and sucrose metabolism

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