PKC epsilon (PRKCE) Mouse Monoclonal Antibody [Clone ID: OTI1B7]

CAT#: TA502395

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PRKCE (PKC epsilon ) mouse monoclonal antibody, clone OTI1B7 (formerly 1B7)



  View other "OTI1B7" antibodies (4)

USD 379.00


Availability*
In Stock

Size
    • 100 ul


Specifications

Product Data
Clone Name OTI1B7
Applications FC, IF, IHC, WB
Recommended Dilution WB 1:1000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivity Human, Monkey, Dog
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human PRKCE (NP_005391) produced in HEK293T cell.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.95 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 83.5 kDa
Gene Name protein kinase C epsilon
Background Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSeq, Jul 2008]
Synonyms nPKC-epsilon; PKCE
Reference Data
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction

Other Versions

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Recombinant protein of human protein kinase C, epsilon (PRKCE)
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beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
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