AKT2 Mouse Monoclonal Antibody [Clone ID: OTI4H7]

CAT#: TA500814

AKT2 mouse monoclonal antibody, clone OTI4H7 (formerly 4H7)

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 Product Datasheet for 'TA500814'

USD 379


Availability*
In Stock

Size
    • 100 ul

Specifications

Product Data
Clone Name OTI4H7
Applications WB, IHC, IF, FC
Recommend Dilution WB 1:1000, IHC 1:50, IF 1:50~100, FLOW 1:100,
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human AKT2 (NP_001617) produced in HEK293T cell.
Isotype IgG1
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.56 mg/ml
Purification Purified from mouse ascites fluids by affinity chromatography
Predicted Protein Size 55.6 kDa
Gene Name AKT serine/threonine kinase 2
Background This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq].
Synonyms HIHGHH|PKBB|PKBBETA|PRKBB|RAC-BETA
Reference Data
Protein Families Protein Kinase, ES Cell Differentiation/IPS, Druggable Genome
Protein Pathways MAPK signaling pathway, ErbB signaling pathway, Chemokine signaling pathway, mTOR signaling pathway, Apoptosis, VEGF signaling pathway, Focal adhesion, Tight junction, Toll-like receptor signaling pathway, Jak-STAT signaling pathway, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Neurotrophin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Adipocytokine signaling pathway, Pathways in cancer, Colorectal cancer, Renal cell carcinoma, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Melanoma, Chronic myeloid leukemia, Acute myeloid leukemia, Small cell lung cancer, Non-small cell lung cancer
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.