Carbonic Anhydrase IX (CA9) Mouse Monoclonal Antibody [Clone ID: OTI1G7]

CAT#: TA500623

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Anti-CA9 (Carbonic Anhydrase IX) mouse monoclonal antibody, clone OTI1G7 (formerly 1G7)



  View other "OTI1G7" antibodies (4)

USD 379.00


Availability*
In Stock

Size
    • 100 ul


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Specifications

Product Data
Clone Name OTI1G7
Applications FC, IHC, WB
Recommended Dilution WB 1:2000, IHC 1:50, Flow 1:100
Reactivity Human
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Full-length protein expressed in 293T cell transfected with human CA9 expression vector
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 49.7 kDa
Gene Name carbonic anhydrase 9
Background Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-basebalance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.
Synonyms CAIX; MN
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Nitrogen metabolism

Citations (1)

Other Versions

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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