SSX2 Mouse Monoclonal Antibody [Clone ID: OTI4D10]

CAT#: TA500620

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Anti-SSX2 mouse monoclonal antibody, clone OTI4D10 (formerly 4D10)



Special Offer: Try sample size of this antibody at $99/€99. Use code "TrueSample".

USD 447.00


Availability*
In Stock

Size
    • 100 ul


Specifications

Product Data
Clone Name OTI4D10
Applications IF, IHC, WB
Recommended Dilution WB 1:2000, IHC 1:50, IF 1:100
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full-length protein expressed in 293T cell transfected with human SSX2 expression vector
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.67 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 21.6 kDa
Gene Name SSX family member 2
Background The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.
Synonyms CT5.2; CT5.2A; HD21; HOM-MEL-40; SSX
Reference Data
Protein Families Druggable Genome, Transcription Factors
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