DHFR Mouse Monoclonal Antibody [Clone ID: OTI6G7]

CAT#: TA500543S

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Anti-DHFR (Dihydrofolate reductase) mouse monoclonal antibody, clone OTI6G7 (formerly 6G7)


Product Datasheet for 'TA500543S'


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USD 159.00


Availability*
2 Days

Size
    • 30 ul


Specifications

Product Data
Clone Name OTI6G7
Applications IF, IHC, WB
Recommend Dilution WB 1:2000 IHC 1:50 IF 1:100
Reactivity Human, Monkey, Dog
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full-length protein expressed in 293T cell transfected with human DHFR expression vector
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from cell culture supernatant by affinity chromatography
Predicted Protein Size 21.5 kDa
Gene Name dihydrofolate reductase
Background Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia.
Synonyms DHFRP1; DYR
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Folate biosynthesis, Metabolic pathways, One carbon pool by folate

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