TRIB2 Mouse Monoclonal Antibody [Clone ID: OTI8D11]

CAT#: TA500510

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TRIB2 mouse monoclonal antibody, clone OTI8D11 (formerly 8D11)

Size: 30 ul 100 ul

Formulation: Standard Carrier-Free

Conjugation: Unconjugated Biotin HRP



USD 478.00

In Stock*

Size
    • 100 ul

Frequently bought together (3)
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Specifications

Product Data
Clone Name OTI8D11
Applications FC, IF, IHC, WB
Recommended Dilution WB 1:1000~2000, IHC 1:50, IF 1:50, FLOW 1:100
Reactivities Human, Mouse
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Full length human recombinant protein of human TRIB2 (NP_067675) produced in HEK293T cell.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 38.8 kDa
Gene Name tribbles pseudokinase 2
Background This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene.
Synonyms C5FW; GS3955; TRB2
Reference Data
Protein Families Druggable Genome, Protein Kinase
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