LAT2 (SLC7A8) Mouse Monoclonal Antibody [Clone ID: OTI5A9]
Specifications
| Product Data | |
| Clone Name | OTI5A9 |
|---|---|
| Application | FC, IF, IHC, IP, WB |
| Recommended Dilution | WB 1:500~2000, IHC 1:50, IF 1:100, FLOW 1:100, IP 2ug/500ul |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full-length protein expressed in 293T cell transfected with human SLC7A8 expression vector . |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 58.4 kDa |
| Gene Name | solute carrier family 7 member 8 |
| Database Link | |
| Background | Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine orD,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney. |
| Synonyms | LAT2; LPI-PC1 |
| Note | WB application: Only overexpression results are guaranteed, not endogenous |
| Reference Data | |
| Protein Categories | Membrane Proteins |
| Protein Families | Druggable Genome, Transmembrane |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI5A9" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF500503 | Carrier-free (BSA/glycerol-free) SLC7A8 mouse monoclonal antibody, clone OTI5A9 (formerly 5A9) | 100 ug |
$620.00
|
|
| TA500503AM | Anti-SLC7A8 (LAT2) mouse monoclonal antibody, clone OTI5A9 (formerly 5A9), Biotinylated | 100 ul |
$509.00
|
|
| TA500503BM | Anti-SLC7A8 (LAT2) mouse monoclonal antibody, clone OTI5A9 (formerly 5A9), HRP conjugated | 100 ul |
$509.00
|
|
| TA500503S | Anti-SLC7A8 (LAT2) mouse monoclonal antibody, clone OTI5A9 (formerly 5A9) | 30 ul |
$200.00
|
|
Citations
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.