Glucokinase (GCK) Mouse Monoclonal Antibody [Clone ID: OTI3E3]
CAT#: TA500459
GCK mouse monoclonal antibody, clone OTI3E3 (formerly 3E3)
Size: 30 ul
Formulation: Carrier-Free
USD 436.00
USD 867.00
Specifications
Product Data | |
Clone Name | OTI3E3 |
Applications | IF, IHC, WB |
Recommended Dilution | WB 1:500, IHC 1:50, IF 1:50 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human GCK (NP_000153) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 52 kDa |
Gene Name | glucokinase |
Database Link | |
Background | Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI). [provided by RefSeq] |
Synonyms | FGQTL3; GK; GLK; HHF3; HK4; HKIV; HXKP; LGLK; MODY2 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Amino sugar and nucleotide sugar metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Insulin signaling pathway, Maturity onset diabetes of the young, Metabolic pathways, Starch and sucrose metabolism, Type II diabetes mellitus |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF500459 | Carrier-free (BSA/glycerol-free) GCK mouse monoclonal antibody, clone OTI3E3 (formerly 3E3) |
USD 600.00 |
|
TA500459AM | GCK mouse monoclonal antibody, clone 3E3, Biotinylated |
USD 509.00 |
|
TA500459BM | GCK mouse monoclonal antibody, clone 3E3, HRP conjugated |
USD 509.00 |
|
TA500459S | GCK mouse monoclonal antibody, clone OTI3E3 (formerly 3E3) |
USD 200.00 |
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