MEK4 (MAP2K4) Mouse Monoclonal Antibody [Clone ID: OTI4B4]

CAT#: TA500411

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Anti-MAP2K4 (MEK4) mouse monoclonal antibody, clone OTI4B4 (formerly 4B4)


Product Datasheet for 'TA500411'


  View other "OTI4B4" antibodies (2)

USD 379.00


Availability*
In Stock

Size
    • 100 ul


Specifications

Product Data
Clone Name OTI4B4
Applications FC, IF, IHC, IP, WB
Recommended Dilution WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100, IP 2ug/500ul
Reactivity Human
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Full-length protein expressed in 293T cell transfected with human MAP2K4 expression vector
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1.09 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 44.3 kDa
Gene Name mitogen-activated protein kinase kinase 4
Background This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver.
Synonyms JNKK; JNKK1; MAPKK4; MEK4; MKK4; PRKMK4; SAPKK-1; SAPKK1; SEK1; SERK1; SKK1
Reference Data
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Fc epsilon RI signaling pathway, GnRH signaling pathway, MAPK signaling pathway, Toll-like receptor signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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