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TRPM4 Mouse Monoclonal Antibody [Clone ID: OTI3C4]

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SKU
TA500370
Anti-TRPM4 mouse monoclonal antibody, clone OTI3C4 (formerly 3C4)
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
In Stock*
Bulk/Customize

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View other "TRPM4 or NM_017636" antibodies

Specifications
Specifications
Product Data
Clone Name OTI3C4
Application WB
Recommended Dilution WB 1:2000
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full-length protein expressed in 293T cell transfected with human TRPM4 expression vector
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1.2 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 134.3 kDa
Gene Name transient receptor potential cation channel subfamily M member 4
Database Link
Background Calcium-activated non selective (CAN) cation channel that mediates membrane depolarization. While it is activated by increase in intracellular Ca(2+), it is impermeable to it. Mediates transport of monovalent cations (Na(+) > K(+) > Cs(+) > Li(+)), leading to depolarize the membrane. It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc. Participates in T-cell activation by modulating Ca(2+) oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production. Involved in myogenic constriction of cerebral arteries. Controls insulin secretion in pancreatic beta-cells. May also be involved in pacemaking or could cause irregular electrical activity under conditions of Ca(2+) overload
Synonyms hTRPM4; LTrpC4; PFHB1B; TRPM4B
Reference Data
Protein Categories Cardiovascular diseases, Cytokines, Intracellular Proteins, Membrane Proteins
Protein Families Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane
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Resources
Other "OTI3C4" antibodies (4)
SKU Description Size Price
CF500370 Carrier-free (BSA/glycerol-free) TRPM4 mouse monoclonal antibody, clone OTI3C4 (formerly 3C4) 100 ug
$620.00
TA500370AM Anti-TRPM4 mouse monoclonal antibody, clone OTI3C4 (formerly 3C4), Biotinylated 100 ul
$509.00
TA500370BM Anti-TRPM4 mouse monoclonal antibody, clone OTI3C4 (formerly 3C4), HRP conjugated 100 ul
$509.00
TA500370S Anti-TRPM4 mouse monoclonal antibody, clone OTI3C4 (formerly 3C4) 30 ul
$200.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.