VEGF Mouse Monoclonal Antibody [Clone ID: OTI2F7]

CAT#: TA500288

anti-VEGFA (VEGF) mouse monoclonal antibody, clone OTI2F7 (formerly 2F7)

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 Product Datasheet for 'TA500288'

USD 350


Availability*
In Stock

Size
    • 100 ul

Specifications

Product Data
Clone Name OTI2F7
Applications WB, IHC
Recommend Dilution WB 1:1000, IHC 1:50
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Recombinant protein expressed in E.coli corresponding to amino acids 27-233 of human VEGF
Isotype IgG2b
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.8 mg/ml
Purification Purified from mouse ascites fluids by affinity chromatography
Predicted Protein Size 23.8 kDa
Gene Name vascular endothelial growth factor A
Background VEGF is a member of the PDGF/VEGF growth factor family that is often found as a disulfide linked homodimer. It is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in VEGF gene have been associated with proliferative and nonproliferative diabetic retinopathy.
Synonyms MVCD1|VEGF|VPF
Reference Data
Protein Families Secreted Protein, Druggable Genome
Protein Pathways Cytokine-cytokine receptor interaction, mTOR signaling pathway, VEGF signaling pathway, Focal adhesion, Pathways in cancer, Renal cell carcinoma, Pancreatic cancer, Bladder cancer
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.