AFGF Mouse Monoclonal Antibody [Clone ID: OTI4D2]
aFGF (FGF1) mouse monoclonal antibody, clone OTI4D2 (formerly 4D2)
Product Datasheet for 'TA500064'
|Recommend Dilution||WB 1:5000~50000, IF 1:100|
|Immunogen||Human recombinant protein fragment corresponding to amino acids 16-155 of human AFGF (NP_000791) produced in E.coli.|
|Formulation||PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purification||Purified from cell culture supernatant by affinity chromatography|
|Predicted Protein Size||15.8 kDa|
|Gene Name||fibroblast growth factor 1|
|Background||FGF1 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Three alternatively spliced variants encoding different isoforms have been described.|
|Synonyms||AFGF; ECGF; ECGF-beta; ECGFA; ECGFB; FGF-1; FGF-alpha; FGFA; GLIO703; HBGF-1; HBGF1|
|Protein Families||Druggable Genome, Secreted Protein|
|Protein Pathways||MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.