PDX1 Mouse Monoclonal Antibody [Clone ID: OTI5D5]

CAT#: TA500039

Pdx1 mouse monoclonal antibody, clone OTI5D5 (formerly 5D5)

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 Product Datasheet for 'TA500039'

USD 379

In Stock

    • 100 ul

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Product Data
Clone Name OTI5D5
Applications WB
Recommend Dilution WB 1:5000~10000,
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human PDX1 (NP_000200) produced in E.coli.
Isotype IgG1
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1.00mg/ml
Purification Purified from cell culture supernatant by affinity chromatography
Predicted Protein Size 30.6 kDa
Gene Name pancreatic and duodenal homeobox 1
Background Pdx1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. It is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in PDX1 gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
Reference Data
Protein Families ES Cell Differentiation/IPS, Embryonic stem cells, Induced pluripotent stem cells, Transcription Factors
Protein Pathways Type II diabetes mellitus, Maturity onset diabetes of the young
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.