Oct4 (POU5F1) Mouse Monoclonal Antibody [Clone ID: OTI9B7]
OCT4 mouse monoclonal antibody, clone OTI9B7 (formerly 9B7)
Product Datasheet for 'TA500035'
|Applications||IF, IHC, WB|
|Recommend Dilution||WB 1:5000, IHC 1:50, IF 1:100|
|Immunogen||Full length human recombinant protein of human POU5F1 (NP_002692) produced in E.coli.|
|Formulation||PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purification||Purified from mouse ascites fluids by affinity chromatography|
|Predicted Protein Size||38.4 kDa|
|Gene Name||POU class 5 homeobox 1|
|Background||This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.|
|Synonyms||Oct-3; Oct-4; OCT3; OCT4; OTF-3; OTF3; OTF4|
|Protein Families||Adult stem cells, Cancer stem cells, Embryonic stem cells, Induced pluripotent stem cells, Stem cell - Pluripotency, Transcription Factors|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.