BFGF Mouse Monoclonal Antibody [Clone ID: OTI2H11]

CAT#: TA500013

bFGF (FGF2) mouse monoclonal antibody, clone OTI2H11 (formerly 2H11)

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 Product Datasheet for 'TA500013'

USD 350.00


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In Stock

Size
    • 100 ul

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Specifications

Product Data
Clone Name OTI2H11
Applications WB
Recommend Dilution WB 1:5000~10000,
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 10-155 of human bFGF (NP_001997) produced in E.coli.
Isotype IgG1
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Reconstitution Method Reconstitute with PBS (pH7.3). To use this carrier-free antibody for conjugation experiment, we strongly recommend you to perform another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Concentration 1.00mg/ml
Purification Purified from cell culture supernatant by affinity chromatography
Predicted Protein Size 30.6 kDa
Gene Name fibroblast growth factor 2
Background BFGF is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
Synonyms BFGF|FGF-2|FGFB|HBGF-2
Reference Data
Protein Families Secreted Protein, Druggable Genome
Protein Pathways MAPK signaling pathway, Regulation of actin cytoskeleton, Pathways in cancer, Melanoma
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