Plasma Kallikrein 1B (KLKB1) Rabbit Monoclonal Antibody
| Product Data | |
| Application | IHC, IP, WB |
|---|---|
| Recommended Dilution | WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50 |
| Reactivity | Human, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | A synthesized peptide derived from human KLKB1 |
| Specificity | KLKB1 Antibody detects endogenous levels of total KLKB1 |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration | lot specific |
| Purification | Affinity-chromatography |
| Conjugation | Unconjugated |
| Storage | Store at +4°C short term. Store at -23°C long term. Avoid freeze / thaw cycle. |
| Shipping | Blue Ice |
| Predicted Protein Size | 80kDa |
| Gene Name | kallikrein B1 |
| Database Link | |
| Background | The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin. |
| Synonyms | Fletcher factor; Kallikrein B1; kallikrein B plasma; Kininogenin; KLK3; KLKB1; PKK; PKKD; Plasma kallikrein light chain; PPK; Prekallikrein |
| Reference Data | |
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