HSP27 (HSPB1) Rabbit Monoclonal Antibody
| Product Data | |
| Application | IP, WB |
|---|---|
| Recommended Dilution | WB 1:500~1:1000 IP 1:50 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | A synthesized peptide derived from human Phospho-Hsp27 (S82) |
| Specificity | Phospho-Hsp27 (S82) Antibody detects endogenous levels of Phospho-Hsp27 (S82) |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration | lot specific |
| Purification | Affinity-chromatography |
| Conjugation | Unconjugated |
| Storage | Store at +4°C short term. Store at -22°C long term. Avoid freeze / thaw cycle. |
| Shipping | Blue Ice |
| Predicted Protein Size | 27kDa |
| Gene Name | heat shock protein family B (small) member 1 |
| Database Link | |
| Background | Heat shock protein (HSP) 27 is one of the small HSPs that are constitutively expressed at different levels in various cell types and tissues. Like other small HSPs, HSP27 is regulated at both the transcriptional and posttranslational levels. In response to stress, the HSP27 expression increases several-fold to confer cellular resistance to the adverse environmental change. HSP27 is phosphorylated at Ser15, Ser78, and Ser82 by MAPKAPK-2 as a result of the activation of the p38 MAP kinase pathway. |
| Synonyms | 28 kDa heat shock protein; Estrogen-regulated 24 kDa protein; Growth-related 25 kDa protein; Heat shock 27 kDa protein; HSP25; HSP 27; HSPB1; P25; SRP27; Stress-responsive protein 27 |
| Reference Data | |
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