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Phospho Tau (Thr231) Rabbit Monoclonal Antibody [Clone ID: OTIRA0405]

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SKU
TA422586
Phospho-Tau (T231) Antibody
Size:
100 ul
Conjugation:
Unconjugated
  $480.00
4 Weeks*
Bulk/Customize

View other "Phospho Tau (Thr231)" antibodies

Specifications
Specifications
Product Data
Clone Name OTIRA0405
Application IHC, IP, WB
Recommended Dilution WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Monoclonal
Immunogen A synthesized peptide derived from human Phospho-Tau (T231)
Specificity Phospho-Tau (T231) Antibody detects endogenous levels of Phospho-Tau (T231)
Buffer Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Concentration lot specific
Purification Affinity-chromatography
Conjugation Unconjugated
Storage Store at +4°C short term. Store at -22°C long term. Avoid freeze / thaw cycle.
Shipping Blue Ice
Predicted Protein Size 46kDa
Gene Name microtubule associated protein tau
Database Link
Background Tau is a heterogeneous microtubule-associated protein that promotes and stabilizes microtubule assembly, especially in axons. Six isoforms with different amino-terminal inserts and different numbers of tandem repeats near the carboxy-terminus have been identified, and tau is hyperphosphorylated at approximately 25 sites by ERK, GSK-3 and CDK5. Phosphorylation decreases the ability of tau to bind to microtubules. Neurofibrillary tangles are a major hallmark of Alzheimer's disease and these tangles are bundles of paired helical filaments composed of hyperphosphorylated tau.
Synonyms MAPT; Microtubule-associated protein tau; MTBT1; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau
Reference Data
Protein Categories Growth Factors, Intracellular Proteins, Nervous system: Neurodegenerative diseases, Secreated Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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