SGK1 Rabbit Monoclonal Antibody
Product Data | |
Application | FC, IHC, IP, WB |
---|---|
Recommended Dilution | WB 1:500~1:1000 IHC 1:50~1:200 IP 1:50 FC 1:30 |
Reactivity | Human, Mouse, Rat |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Monoclonal |
Immunogen | A synthesized peptide derived from human SGK1 |
Specificity | SGK1 Antibody detects endogenous levels of SGK1 |
Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Concentration | lot specific |
Purification | Affinity-chromatography |
Conjugation | Unconjugated |
Storage | Store at +4°C short term. Store at -23°C long term. Avoid freeze / thaw cycle. |
Shipping | Blue Ice |
Predicted Protein Size | 57kDa |
Gene Name | serum/glucocorticoid regulated kinase 1 |
Database Link | |
Background | Serum and glucocorticoid-inducible kinase (SGK) is a serine/threonine kinase closely related to Akt. SGK is rapidly induced in response to a variety of stimuli, including serum, glucocorticoid, follicle stimulating hormone, osmotic shock, and mineralocorticoids. SGK activation can be accomplished via HGF PI3K-dependent pathways and by integrin-mediated PI3K-independent pathways. Induction and activation of SGK has been implicated in activating the modulation of anti-apoptotic and cell cycle regulation. |
Synonyms | EC 2.7.11.1; kinase SGK; Serum/glucocorticoid-regulated kinase; SGK; Sgk; SGK1; Sgk1 |
Reference Data |
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