SC35 (SRSF2) Rabbit Monoclonal Antibody [Clone ID: R04-7J2]

CAT#: TA385322

SC35 Rabbit monoclonal Antibody


USD 380.00

4 Weeks*

Size
    • 100 ul

Product Images

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Specifications

Product Data
Clone Name R04-7J2
Applications IHC, IP, WB
Recommended Dilution WB: 1/1000
IHC: 1/200
IP: 1/20
Reactivities Human, Rat
Host Rabbit
Isotype IgG
Clonality Monoclonal
Immunogen A synthetic peptide of human SC35
Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration lot specific
Purification Affinity Purified
Conjugation Unconjugated
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Stability 1 year
Predicted Protein Size Calculated MW: 26 kDa; Observed MW: 35 kDa
Gene Name serine/arginine-rich splicing factor 2
Background Swiss-Prot Acc.Q01130.Necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5'-GTTCGAGTA-3'. Can bind to beta-globin mRNA and commit it to the splicing pathway. The phosphorylated form (by SRPK2) is required for cellular apoptosis in response to cisplatin treatment.
Synonyms D11Wsu175e; MRF-1; Pr264; SC35; Sfrs2; Sfrs10
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.