Phospho Tau (Thr205) Rabbit Monoclonal Antibody [Clone ID: R07-4A8]
Specifications
| Product Data | |
| Clone Name | R07-4A8 |
|---|---|
| Application | WB |
| Recommended Dilution | WB:1/2000-5000 |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Thr205 of human Tau (Phosphorylated) |
| Buffer | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Concentration | lot specific |
| Purification | Affinity Purified |
| Conjugation | Unconjugated |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Stability | 1 year |
| Shipping | Blue Ice |
| Predicted Protein Size | Calculated MW: 79 kDa; Observed MW: 50-80 kDa |
| Gene Name | microtubule associated protein tau |
| Database Link | |
| Background | Swiss-Prot Acc.P10636.Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. |
| Synonyms | DDPAC; FLJ31424; FTDP-17; MAPTL; MGC138549; MSTD; MTBT1; MTBT2; PHF-tau; PPND; TAU |
| Reference Data | |
| Protein Categories | Growth Factors, Intracellular Proteins, Nervous system: Neurodegenerative diseases, Secreated Proteins |
Reviews
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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