H3FT (HIST3H3) Rabbit Polyclonal Antibody
| Product Data | |
| Application | ICC/IF, IHC, WB |
|---|---|
| Recommended Dilution | WB,1:500 - 1:2000 IHC,1:50 - 1:200 IF,1:50 - 1:200 |
| Reactivity | Human, Mouse, Other (Wide Range), Rat |
| Modification | Phospho S10 |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | A synthetic phosphorylated peptide around S10 of human Histone H3 (NP_003484.1). |
| Buffer | PBS with 0.09% Sodium azide,50% glycerol,pH7.3. |
| Concentration | lot specific |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Stability | Shelf life: one year from despatch. |
| Predicted Protein Size | 15kDa |
| Gene Name | histone cluster 3, H3 |
| Database Link | |
| Background | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. |
| Synonyms | H3.4; H3/g; H3/t; H3FT; H3t; MGC126886; MGC126888 |
| Reference Data | |
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