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Cannabinoid Receptor I (CNR1) Rabbit Polyclonal Antibody
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Specifications
| Product Data | |
| Applications | IHC |
| Recommended Dilution | IHC: 20-100 Positive control: Human liver cancer Predicted cell location: Cell membrane |
| Reactivities | Human, Mouse, Rat |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human CNR1 |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C. |
| Stability | 1 year |
| Gene Name | cannabinoid receptor 1 (brain) |
| Database Link | |
| Background | This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. |
| Synonyms | CANN6; CB-R; CB1; CB1A; CB1K5; CB1R; CNR; OTTHUMP00000016838; OTTHUMP00000016839 |
| Reference Data | |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.