PPP2R1A Rabbit Polyclonal Antibody

CAT#: TA370661

PPP2R1A rabbit polyclonal antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane: NIH/3T3 cell lysate Primary antibody: TA370661 (PPP2R1A Antibody) at dilution 1/850 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 3 seconds

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA370661 (PPP2R1A Antibody) at dilution 1/65 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA370661 (PPP2R1A Antibody) at dilution 1/65, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1000-5000
  WB positive control: NIH/3T3 cell lysate
  IHC: 70-350
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human PPP2R1A
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 65 kDa
• Gene Name: protein phosphatase 2 scaffold subunit Aalpha
• Database Link:
  Entrez Gene 5518 Human
  UniProt ID P30153
• Background: This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described.
• Synonyms: MGC786; PR65A