THOC7 Rabbit Polyclonal Antibody

SKU TA358975

THOC7 Antibody - C-terminal region

Product Data

• Application: WB
• Reactivity: Human
• Antibody Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human THOC7
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Pig, Rabbit, Rat; Homology: Cow: 100%; Dog: 93%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Pig: 93%; Rabbit: 79%; Rat: 79%
• Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.; Note that this product is shipped as lyophilized powder to China customers.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Predicted Protein Size: 22kDa
• Gene Name: THO complex 7
• Database Link:
  NP_079351
  Q6I9Y2
• Background: THOC7 is required for efficient export of polyadenylated RNA. It acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.
• Synonyms: FLJ23445; fSAP24; hTREX30; NIF3L1BP1

Reference Data