Bak (BAK1) Rabbit Polyclonal Antibody

CAT#: TA355446

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BAK1 Antibody - N-terminal region



USD 539.00


Availability*
5 Days

Size
    • 100 ul


Product images

Specifications

Product Data
Applications WB
Reactivities Human
Host Rabbit
Clonality Polyclonal
Specificity Expected reactivity: Horse, Human
Homology: Horse: 80%; Human: 100%
Formulation Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration lot specific
Purification Affinity Purified
Conjugation Unconjugated
Storage For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Stability Shelf life: one year from despatch.
Predicted Protein Size 23kDa
Gene Name BCL2 antagonist/killer 1
Background BAK1 belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
Synonyms BAK; BAK-LIKE; Bcl2-L-7; BCL2L7; CDN1; MGC3887; MGC117255
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency, Transmembrane
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