Cytochrome P450 3A4 (CYP3A4) Sheep Polyclonal Antibody

CAT#: TA353133L

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Sheep polyclonal anti-Cytochrome P450 3A4 antibody



USD 1,255.00


Availability*
5 Days

Size
    • 500 ul


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Specifications

Product Data
Recommended Dilution WB
Reactivity Human
Host Sheep
Isotype IgG
Clonality Polyclonal
Immunogen CYP 3A4
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name cytochrome P450 family 3 subfamily A member 4
Background This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1.
Synonyms CP33; CP34; CYP3A; CYP3A3; CYPIIIA3; CYPIIIA4; HLP; NF-25; P450C3; P450PCN1
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, P450, Transmembrane
Protein Pathways Drug metabolism - cytochrome P450, Drug metabolism - other enzymes, Linoleic acid metabolism, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Retinol metabolism
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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