Silencer of Death Domain (BAG4) Rabbit Polyclonal Antibody

CAT#: TA351743

Rabbit Polyclonal Anti-BAG4 rabbit polyclonal antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 60 μg Lane: Human normal stomach tissue Primary antibody: TA351743 (BAG4 Antibody) at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 7 minutes

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Human normal stomach tissue
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human BAG4
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 50 kDa
• Gene Name: BCL2 associated athanogene 4
• Database Link:
  NP_004865
  Entrez Gene 67384 MouseEntrez Gene 9530 Human
  UniProt ID O95429
• Background: The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling.
• Synonyms: BAG-4; SODD

Reference Data

• Protein Families: Druggable Genome