Desmocollin 2 (DSC2) Rabbit Polyclonal Antibody

CAT#: TA351135

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Rabbit Polyclonal Anti-DSC2 Antibody

Product Datasheet for 'TA351135'

USD 345.00

In Stock

    • 100 ul

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Product Data
Applications IHC
Recommended Dilution ELISA: 2000-5000, IHC: 50-200
Reactivity Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide of human DSC2
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration 2.3 mg/ml
Purification Antigen affinity purification
Gene Name desmocollin 2
Background The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11.
Synonyms ARVD11; CDHF2; DG2; DGII/III; DSC3
Reference Data
Protein Families Transmembrane
Protein Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC)
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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