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CD30 (TNFRSF8) Rabbit Polyclonal Antibody
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USD 200.00
USD 867.00
USD 665.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommended Dilution | IHC: 100-300 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm |
| Reactivities | Human |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human TNFRSF8 |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Gene Name | tumor necrosis factor receptor superfamily member 8 |
| Database Link | |
| Background | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
| Synonyms | CD30; D1S166E; Ki-1 |
| Reference Data | |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Stem cell - Pluripotency, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction |
Documents
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| FAQs |
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